ea0081p387 | Endocrine-Related Cancer | ECE2022
Lippert Juliane
, Altieri Barbara
, Morrison Breanna
, Steinhauer Sonja
, Smith Gabrielle
, Lorey Antonia
, Hanna Urlaub
, Kircher Stefan
, Sitch Alice J
, Fassnacht Martin
, Ronchi Cristina
Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine neoplasia with heterogeneous molecular background and clinical outcome. Previous studies identified hypermethylation in specific genes to be associated with poor prognosis. Here, we aimed to investigate the role of methylation pattern for prognostic stratification of patients with ACC as compared to clinical parameters, using methods easily applicable in clinical routine. We investigated a total of 237 ACCs (96 ...